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KMID : 0857020100250010102
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Kosin Medical Journal
2010 Volume.25 No. 1 p.102 ~ p.105
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Acute Pancreatitis Developed after Histoacryl InjectionTheraphy in Active Duodenal Ulcer Bleeding
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Yoo Jae-Hoon
Moon Won
Roh Ji-Hun
Goo Dong-Young
Jo Yeong-Hwa
Kim Ki-Su
Yoon Jun-Mo
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Abstract
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Upper gastrointestinal bleeding is common and potentially life threatening medical emergency. Emergency endoscopy
is the first choice of diagnostic and treatment measure for patients with active upper gastrointestinal bleeding. Histoacryl
should be considered a second-line treatment modality when conventional treatments were failed. However, it might
cause several complications. Herein, we report a case of acute pancreatitis developed after histoacryl injection therapy
for active duodenal ulcer bleeding. A 71-year-old man was admitted with melena and hematemesis. On emergency
endoscopy, a 2 cm sized active ulcer with bleeding from an exposedvessel was seen at the duodenal bulb. Attempts
to arrest the bleeding with hemoclipping and submucosal epinephrine injection were tried, but failed. We changed the
method to endoscopic histoacryl injection, and obtained hemostasis immediately. A few hourslater, after successful
hemostasis, patient complained diffuse abdominal pain. Ultrasonography revealed hyperechoic heterogenous diffuse
pancreatic enlargement and right pararenal space fluid collection, this ultrasonographic findings and elevated serum
pancreatic enzymes are compatible with acute pancreatitis.
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KEYWORD
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Histoacryl, Peptic Ulcer, Hemorrhage, Pancreatitis
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